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OriGene TissueScan in recent publications
Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells Brain, Jul 2010; 133: 1961 - 1972 [Brain Cancer Panel I ]
Global analysis of microarray data reveals intrinsic properties in gene expression and tissue selectivity Bioinformatics, Jul 2010; 26: 1723 - 1730. [Cancer Survey Panel 384 - I ]
Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy Brain, Jul 2010; 133: 2123 - 2135 [HSCA101]
CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592 European Journal of Human Genetics (9 June 2010) doi:10.1038/ejhg.2010.82 Article []

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Advanced Tools for Cancer Biomarker Discovery and Validation

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As a gene-centric company, OriGene has developed unique technologies and products for cancer biomarker discovery and validation

  1. Most comprehensive human cancer tissue biorepository
    • >140,000 tissue collections
    • Collected under strict IRB and ethical consenting practices
    • Annotated with associated clinical data
  2. TissueScan Cancer qPCR Arrays – mRNA expression profiling
    • Panels of normalized cDNA prepared from tumor tissues, ready for qPCR
    • Broad tumor coverage – Multiple panels for breast, colon, lung, ovarian, and prostate cancers
    • Convenient and fast – qPCR ready format; results in less than 2 hours.
  3. ProteoScan Cancer Lysate Arrays – protein expression profiling
    • High-density reverse-phase protein arrays (RPPA) spotted with cancer and normal tissue lysates
    • 432 tissue lysates from pathologist-verified normal and cancer specimens
    • 11 cancers represented (25 cancer samples +15 normal samples per cancer type)
  4. Multiplex microRNA Detection Assays
    • xMAP® multiplex bead array allows analysis of up to 100 microRNAs in one sample
    • 96-well format allows for hundreds of samples profiled in one day
    • Genome wide coverage
  5. Multiplex Transcription Factor Assays
    • xMAP® multiplex bead array allows analysis of up to 50 transcription factors in one sample
    • Unparalled speed of data acquisition - ~2,000 results in 3 hours
    • Multiple binding sites in assay mimics in vivo binding conditions
  6. Cancer-pathway specific qPCR primer Panels
    • 21 pre-designed key cancer pathways
    • qPCR screening-ready format
    • Custom panels available

 

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