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OriGene shRNA in recent publications
Enhancement of Autophagy during Lytic Replication by the Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Activator J. Virol., Aug 2010; 84: 7448 - 7458 [BECN1]

Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53 Mol. Cell. Biol., Aug 2010; 30: 3981 - 3993 [MYB ]

GPR103b Functions in the Peripheral Regulation of Adipogenesis Mol. Endocrinol., Aug 2010; 24: 1615 - 1625 []

Identification of Small Molecules That Suppress MicroRNA Function and Reverse Tumorigenesis J. Biol. Chem., Aug 2010; 285: 24707 - 24716 [pRS]

Exact-shRNA: Customized shRNA service

Exact-shRNA is an shRNA service for the special needs outside our pre-designed shRNA products. Examples are

  • shRNA targeting species other than Human, Mouse or Rat
  • Integrate an effective siRNA oligo sequence into an shRNA vector
  • Isoform-specific knock down
  • Have shRNA constructs that target multiple species
  • Reproduce a published result where shRNA sequence is available/disclosed

There are two modes of service with Exact-shRNA:

  • Self-design: Customers specify the short hairpin sequences (stem and loop) and OriGene constructs the vector. This is targeted to researchers who have gained knowledge of the effective target sequence, either from previous research or from published work. Up to 4 constructs are allowed for each project. Additional constructs can be submitted as a new project.
  • OriGene-design: Customers define the transcript sequence(s) and OriGene designs the shRNA (stem and loop) using our proprietary algorithm. Four constructs will be designed whenever possible.
Click here to fill out the Exact-shRNA Request Form. When placing an order, just refer to the catalog number on the request form.

If you would like some assistance in the design of your shRNA constructs, we have experienced molecular biologists in our technical support team ready to help. Contact the Exact-shRNA team at 301.340.3188 option 2.

Useful Links

Manual Vector Application FAQ Citation


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