OriGene shRNA in recent publications

Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis PLoS ONE. 2009; 4(5): e5467 [Spry4(in vivo application)]

RNA interference-mediated in vivo silencing of FasL as a strategy for the enhancement of DNA vaccine potency Human Gene Therapy. August 2008, 19(8): 763-773 [sh-Luc(in vivo application)]

ZIP4 Regulates Pancreatic Cancer Cell Growth by Activating IL-6/STAT3 Pathway through Zinc Finger Transcription Factor CREB Clin. Cancer Res., Mar 2010; 16: 1423 - 1430 [ZIP4]

The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of the Human Cytomegalovirus are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-{kappa}B Sites in Proliferating Cells J. Virol., Feb 2010; 10.1128/JVI.02141-09 [pRS]

HuSH-29: Genome-wide shRNA for Human, Mouse and Rat Genes

Double Gene Knockdown Experiment

Scrambled shRNA (GFP Vector)
+
Scrambled shRNA (RFP Vector)

shRNA against RFP (GFP Vector)
+
shRNA against GFP (RFP Vector)

HuSH-29 are pre-designed shRNA with genome wide coverage (human, mouse and rat) that delivers guaranteed knockdown. The same superior design is also offered for other species through Exact-shRNA.

(Learn more about HuSH-29...)

Features and Benefits

Three retroviral vector options:
- pRS: basic retroviral vector without fluorescence
- pRS with GFP to monitor transfection
- pRS with RFP, ideal for double knockdown
Guaranteed successful gene knockdown (≥70%)
Versatile applications: transient or stable transfection or retroviral infection
As low as $595 for a kit (4 gene-specific shRNA and two negative controls)
5 μg transfection-ready DNA using PowerPrep^® HP Kits

Creating Stable Cell Lines in Double Knockdown Experiments

OriGene now offers new GFP vector with blasticidin selection enabling researchers to create stable cell lines in double gene knockdown experiments. Learn more…

Useful Links

Technical Support

Our scientists will answer your technical questions from 9AM to 7PM ET. Call 1-888-267-4436

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