The application of a broad range of cDNAs and derivative products (shRNA, antibodies) enables scientists to better validate and choose targets that are most relevant to disease processes. Some recent publications describing these methods are listed below for your convenience.

Functional Profiling
Genome-scale functional profiling of the mammalian AP-1 signaling pathway PNAS 2003, 100, 12153-12158, S. Chandra, A. Orth, J. Hogenesch, J. Caldwell, et al.

Genome-Wide shRNA Library Production
A Large-scale RNAi Screen in Human Cells Identifies New Components of the p53 Pathway, Nature 2004, 431-437, K Berns, R. Beijerbergen, R. Bernards, et al.

A resource for large-scale RNA-interference-based screens in mammals, Nature 2004, 427-431, P Paddison, Greg Hannon, et al.

Perfect siRNA Library Construction
Enzymatic production of RNAi libraries from cDNAs, Nature Genetics 2994, 190-196, D Shirane, K Sugao, S Namiki, M Tanabe, M Iino & K Hirose