Monoclonal Antibody Development

Using Human Proteins as Antigens

(TrueMAB™ joint-development program for human proteome)

OriGene subsidizes joint-development programs to generate mouse monoclonal antibodies using human proteins as antigens. Upon the acceptance of the request after OriGene’s evaluation, the participant contributes a portion of the development cost, and OriGene will be responsible for:

• Antigen preparation (human proteins expressed in human cell line with genuine mammalian post-translational modification, purified under native condition)
• Mouse monoclonal antibody development
• Antibody validations (WB on a panel of cell lines, IHC on 24 tissues, IF & ELISA)
• Antibody production & affinity purification

Benefits of the programs:

• Proteins with native conformation will be used as antigens. The protein-derived antibodies recognize native epitopes with high reactivity and specificity compared to peptide-derived antibodies
• Antigens not required, OriGene will prepare the antigens
• OriGene provides extensive characterization data for antibody validation
• OriGene delivers affinity purified antibodies ready for your assays

Program Cost: inquiry (antibody@origene.com)

More information of the TrueMAB™ programs

Monoclonal antibodies for every human protein

TrueMAB™ Antibodies

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