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RNA Interference
RNA interference (RNAi) is a gene-silencing process that targets mRNA hence lowering protein expression. The key RNAi substrates regulating this process are shRNA, miRNA and siRNA. While miRNAs are naturally occurring non-coding small RNAs playing important role in gene-expression regulation, gene-specific shRNAs and siRNAs are powerful tools to effectively knockdown target gene expression. OriGene provides comprehensive and innovative RNAi tools for guaranteed gene silencing.
Pre-designed against human genes.
Pre-designed against human, mouse & rat genes
Pre-designed against human & mouse.
Transfection reagent for siRNA
and plasmid delivery.
Luminex assays for miRNA detection.
Benefits of choosing different RNAi substrates offered by OriGene based on research application
| |
siRNA |
shRNA |
miRNA Expression |
| Gene-Specific Knockdown |
Yes |
Yes |
No, regulates multiple genes |
| Transient Transfection |
Yes |
Yes |
Yes |
| Stable Transfection |
No |
Yes |
Yes |
| Infection |
No |
Yes |
No |
| Performance Guarantee |
Yes |
Yes |
Fully Sequenced |
| Renewable RNAi Resource |
No |
Yes |
Yes |
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